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Article

Frequent hemizygous deletion at 1p36 and hypermethylation downregulate RUNX3 expression in human lung cancer cell lines.

Oncology reports - 1 Oct 2005

Yanada Masashi, Yaoi Takeshi, Shimada Junichi, Sakakura Chouhei, Nishimura Motohiro, Ito Kazuhiro, Terauchi Kunihiko, Nishiyama Katsuhiko, Itoh Kyoko, Fushiki Shinji

Abstract excerpt

Runt-related transcription factor 3 (RUNX3) has been recognized as a tumor suppressor gene in gastric cancer because its expression level was reduced or disappeared due to epigenetic changes. To evaluate the usefulness of the RUNX3 gene as a biomarker of lung cancer, we have analyzed the expression of the RUNX3 gene in 15 lung cancer cell lines by real-time reverse transcription-polymerase chain reaction...

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PMID: 16142337

Genes

RUNX3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Frequent hemizygous deletion at 1p36 and hypermethylation downregulate RUNX3 expression in human lung cancer cell lines.PMID 16142337Read ↗

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