Article
Three distinct regions involved in 3p deletion in human lung cancer.
Oncogene - 1 Mar 1992
Hibi K, Takahashi T, Yamakawa K, Ueda R, Sekido Y, Ariyoshi Y, Suyama M, Takagi H, Nakamura Y, Takahashi T
Abstract excerpt
The 3p deletion was first noted by cytogenetic analysis and was later confirmed by several independent studies using restriction fragment length polymorphism (RFLP) probes. As an initial step towards positional cloning (reverse genetics) of the tumor-suppressor gene(s) on 3p, a detailed analysis...
Topics
- Alleles
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Small Cell
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 3
- DNA, Neoplasm
- Humans
- Lung Neoplasms
- Polymorphism, Restriction Fragment Length