Article
Alterations of BLU, a candidate tumor suppressor gene on chromosome 3p21.3, in human nasopharyngeal carcinoma.
International journal of cancer - 10 Aug 2003
Liu Xiao-Qiong, Chen Han-Kui, Zhang Xiao-Shi, Pan Zhi-Gang, Li Ang, Feng Qi-Sheng, Long Qing-Xin, Wang Xun-Zhang, Zeng Yi-Xin
Abstract excerpt
Nonrandom allelic loss on chromosome 3p is a common event in nasopharyngeal carcinoma (NPC) with the implication that certain tumor suppressor gene(s) in this region are involved in the pathogenesis of these tumors. The BLU gene, located at 3p21.3, has recently been identified as a candidate tumor suppressor gene due to the occurrence of missense mutations and loss of its expression in lung cancer. To investigate...
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