Article
Comparative genomic hybridization analysis detected frequent overrepresentation of chromosome 3q in squamous cell carcinoma of the lung.
Lung cancer (Amsterdam, Netherlands) - 1 Oct 2002
Chujo Masao, Noguchi Tsuyoshi, Miura Takashi, Arinaga Mitsuyuki, Uchida Yuzo, Tagawa Yutaka
Abstract excerpt
The aim of this study was to provide cytogenetic data about squamous cell carcinomas of the lung and to evaluate their characteristic alterations and histogenetic relations. We analyzed 41 squamous cell lung carcinomas by comparative genomic hybridization (CGH) technique. CGH was performed using directly fluorochrome-conjugated DNA. Chromosomal regions where the mean ratio fell below 0.75 were therefore...
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