Article
Frequent homozygous deletions in lung cancer cell lines detected by a DNA marker located at 3p21.3-p22.
Oncogene - 1 Feb 1993
Yamakawa K, Takahashi T, Horio Y, Murata Y, Takahashi E, Hibi K, Yokoyama S, Ueda R, Takahashi T, Nakamura Y
Abstract excerpt
Frequent allelic losses of chromosome 3p in lung cancer have been reported in a number of studies, and we previously demonstrated that 3p21.3 is one of the common regions of deletion in lung cancers and renal cell carcinomas. To further define a region containing the putative tumor suppressor gen...
Topics
- Alleles
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Small Cell
- Chromosomes, Human, Pair 3
- Gene Deletion
- Genes, Suppressor
- Genetic Markers
- Homozygote
- Humans
- Lung Neoplasms
- Tumor Cells, Cultured