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Article

Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma.

World journal of gastroenterology - 1 Feb 2004

Xiao Wen-Hua, Liu Wei-Wen

Abstract excerpt

AIM: To analyze the genetic and epigenetic alterations of RUNX3 gene, a potential putative tumor suppressor gene, in hepatocellular carcinoma (HCC). METHODS: PCR-based loss of heterozygosity (LOH) detection, analysis of mutation with PCR-single strand conformational polymorphism (SSCP) and sequencing, and methylation study with methylation specific PCR (MSP) were performed on RUNX3 gene in a series of 62 HCCs...

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Source

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Identifiers

PMID: 14760761
DOI: 10.3748/wjg.v10.i3.376
PMCID: PMC4724901

Genes

RUNX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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