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Article

Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila.

Current biology : CB - 6 Sept 2005

Bhalerao Sheetal, Berdnik Daniela, Török Tibor, Knoblich Juergen A

Abstract excerpt

During asymmetric cell division, protein determinants are segregated into one of the two daughter cells. The Numb protein acts as a segregating determinant during both mouse and Drosophila development. In flies, Numb localizes asymmetrically and is required for cell-fate specification in the central and peripheral nervous systems, as well as during muscle and heart development. Whether its asymmetric segregation...

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Source

Identifiers

PMID: 16139215
DOI: 10.1016/j.cub.2005.07.061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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