Article
Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast.
Nature - 30 Nov 2000
Ohshiro T, Yagami T, Zhang C, Matsuzaki F
Abstract excerpt
Cellular diversity during development arises in part from asymmetric divisions, which generate two distinct cells by transmitting localized determinants from a progenitor cell into one daughter cell. In Drosophila, neuroblasts undergo typical asymmetric divisions to produce another neuroblast and a ganglion mother cell. At mitosis, neural fate determinants, including Prospero and Numb, localize to the basal...
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