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Article

Segregation of myogenic lineages in Drosophila requires numb.

Development (Cambridge, England) - 1 Dec 1997

Ruiz Gómez M, Bate M

Abstract excerpt

Terminal divisions of myogenic lineages in the Drosophila embryo generate sibling myoblasts that found larval muscles or form precursors of adult muscles. Alternative fates adopted by sibling myoblasts are associated with distinct patterns of gene expression. Genes expressed in the progenitor cell are maintained in one sibling and repressed in the other. These differences depend on an asymmetric segregation of...

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Source

Identifiers

PMID: 9428422
DOI: 10.1242/dev.124.23.4857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Segregation of myogenic lineages in Drosophila requires numb.PMID 9428422Read ↗

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Notch regulates numb: integration of conditional and autonomous cell fate specification.Semantic proximity Read ↗

Numb antagonizes Notch signaling to specify sibling neuron cell fates.Semantic proximity Read ↗

Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors.Semantic proximity Read ↗

Binary sibling neuronal cell fate decisions in the Drosophila embryonic central nervous system are nonstochastic and require inscuteable-mediated asymmetry of ganglion mother cells.Semantic proximity Read ↗

Numb Suppresses Notch-Dependent Activation of Enhancer of split during Lateral Inhibition in the Drosophila Embryonic Nervous System.Semantic proximity Read ↗

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