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Article

The enigma of the numb-Notch relationship during mammalian embryogenesis.

Developmental neuroscience - 1 Jan 2006

Petersen Petur H, Tang Haiyan, Zou Kaiyong, Zhong Weimin

Abstract excerpt

Asymmetric cell division is an attractive means to diversify cell fates during development and for stem cells to balance self-renewal and differentiation. In Drosophila, two signaling pathways, one mediated by Numb and the other by Notch, play essential but antagonistic roles in enabling the two daughters to adopt different fates after a wide variety of asymmetric cell divisions. However, recent studies show that...

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PMID: 16508312
DOI: 10.1159/000090761

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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