Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors.

doi:10.1016/s0092-8674(00)81753-5

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Article

Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors.

Cell - 16 Oct 1998

Lu B, Rothenberg M, Jan L Y, Jan Y N

Abstract excerpt

During mitosis of multiple types of precursor cells in Drosophila, Numb is asymmetrically distributed between the two daughter cells and confers distinct daughter cell fates. Here we report the identification of a novel gene product, Partner of Numb (PON), based on its physical interaction with N...

Topics

Amino Acid Sequence
Animals
Carrier Proteins
Drosophila
Drosophila Proteins
Insect Proteins
Juvenile Hormones
Mesoderm
Mitosis
Molecular Sequence Data
Muscle Fibers, Skeletal
Mutagenesis
Neurons
Phenotype
Protein Binding
Stem Cells

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