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Article

Separate functions of gelsolin mediate sequential steps of collagen phagocytosis.

Molecular biology of the cell - 1 Nov 2005

Arora P D, Chan M W C, Anderson R A, Janmey P A, McCulloch C A

Abstract excerpt

Collagen phagocytosis is a critical mediator of extracellular matrix remodeling. Whereas the binding step of collagen phagocytosis is facilitated by Ca2+-dependent, gelsolin-mediated severing of actin filaments, the regulation of the collagen internalization step is not defined. We determined here whether phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2] regulation of gelsolin is required for collagen...

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Identifiers

PMID: 16120646
DOI: 10.1091/mbc.e05-07-0648
PMCID: PMC1266417

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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