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Article

B-cell receptor translocation to lipid rafts and associated signaling differ between prognostically important subgroups of chronic lymphocytic leukemia.

Cancer research - 15 Aug 2005

Allsup David J, Kamiguti Aura S, Lin Ke, Sherrington Paul D, Matrai Zoltan, Slupsky Joseph R, Cawley John C, Zuzel Mirko

Abstract excerpt

Chronic lymphocytic leukemia (CLL) is a highly heterogeneous disease in which interaction of the malignant cells with antigen is thought to play a key role. Individual CLL-cell clones markedly differ in their ability to respond to B-cell receptor ligation, but the mechanism underlying the frequent hyporesponsiveness is incompletely understood. Our aim was to further clarify the extent and cause of the B-cell...

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PMID: 16103084
DOI: 10.1158/0008-5472.CAN-03-1563

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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