Article
B cell chronic lymphocytic leukemia: lessons learned from studies of the B cell antigen receptor.
Annual review of immunology - 1 Jan 2003
Chiorazzi Nicholas, Ferrarini Manlio
Abstract excerpt
B cell chronic lymphocytic leukemia (B-CLL) is an accumulative disease of slowly proliferating CD5(+) B lymphocytes that develops in the aging population. Whereas some patients with B-CLL have an indolent course and die after many years from unrelated causes, others progress very rapidly and succumb within a few years from this currently incurable leukemia. Over the past decade studies of the structure and...
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