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Article

B-cell receptor signalling in chronic lymphocytic leukaemia

2004-01-01

Abstract excerpt

Chronic lymphocytic leukaemia (CLL) is a highly heterogeneous disease in which interaction with antigen may play a key role. However, individual CLL clones respond differently to B-cell receptor (BCR) ligation, but the relevance of this to disease progression is unclear. The aim of this thesis was to examine BCR function in CLL and define the nature of this characteristic BCR hyporesponsiveness. In chapter 2 the e...

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Literature Corpus work
a44e813e-cd7d-501b-a777-9a40c6737295
DOI
10.17638/03167609
Open publication

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