Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Signaling pathways activated by the B-cell receptor in chronic lymphocytic leukemia

1 Jun 2012

Abstract excerpt

Over the past decade, several features of the B-cell receptor (BCR) complex have emerged as major markers for prognostic classification of B-cell chronic lymphocytic leukemia (B-CLL). In particular, the absence of somatic mutations within the immunoglobulin variable heavy chain genes (IGHV), the presence of ZAP-70 and a higher ability of the BCR to translate signals within the cell have been associated with an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Lymphocytic Leukemia Research
Share to HER2/EGFR in Cancer Research
Share to PI3K/AKT/mTOR signaling in cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22780213
DOI: 10.1586/ehm.12.21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Signaling pathways activated by the B-cell receptor in chronic lymphocytic leukemiaPMID 22780213Read ↗

B-cell receptor signaling in chronic lymphocytic leukemiaSemantic proximity Read ↗

Targeting the B-cell receptor signaling pathway in B lymphoid malignanciesSemantic proximity Read ↗

Old and New Facts and Speculations on the Role of the B Cell Receptor in the Origin of Chronic Lymphocytic LeukemiaSemantic proximity Read ↗

Role of the B-cell receptor in chronic lymphocytic leukemia: where do we stand?Semantic proximity Read ↗

B-cell receptor signaling as a driver of lymphoma development and evolution.Semantic proximity Read ↗

The Meaning and Relevance of B-Cell Receptor Structure and Function in Chronic Lymphocytic LeukemiaSemantic proximity Read ↗

B cell signalling pathways—New targets for precision medicine in chronic lymphocytic leukaemiaSemantic proximity Read ↗

Constitutive Activation of the B Cell Receptor Underlies Dysfunctional Signaling in Chronic Lymphocytic LeukemiaSemantic proximity Read ↗

Molecular heterogeneity in chronic lymphocytic leukemia is dependent on BCR signaling: clinical correlationSemantic proximity Read ↗

The Pathogenesis of Chronic Lymphocytic LeukemiaSemantic proximity Read ↗

Molecular pathogenesis of chronic lymphocytic leukemia: factors and signaling pathways regulating cell growth and survivalSemantic proximity Read ↗

B cell chronic lymphocytic leukemia: lessons learned from studies of the B cell antigen receptor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.