Article
Impaired mitotic progression and preimplantation lethality in mice lacking OMCG1, a new evolutionarily conserved nuclear protein.
Molecular and cellular biology - 1 Jul 2005
Artus Jérôme, Vandormael-Pournin Sandrine, Frödin Morten, Nacerddine Karim, Babinet Charles, Cohen-Tannoudji Michel
Abstract excerpt
While highly conserved through evolution, the cell cycle has been extensively modified to adapt to new developmental programs. Recently, analyses of mouse mutants revealed that several important cell cycle regulators are either dispensable for development or have a tissue- or cell-type-specific function, indicating that many aspects of cell cycle regulation during mammalian embryo development remain to be...
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