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Article

A conserved triple arginine motif in OMA-1 is required for RNA-binding activity and embryo viability.

RNA (New York, N.Y.) - 16 Oct 2025

Ertekin Asli, Noronha Sharon T, Darko Christable, Massi Francesca, Ryder Sean P

Abstract excerpt

Sexually reproducing organisms make haploid gametes-oocytes and spermatocytes-that combine during fertilization to make an embryo. While both gametes contain similar DNA content, oocytes contain the bulk of the cytoplasm including maternally supplied mRNAs and proteins required prior to zygotic gene activation. RNA-binding proteins are key regulators of these maternal transcripts. In Caenorhabditis elegans, the...

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Identifiers

PMID: 40866298
DOI: 10.1261/rna.080611.125
PMCID: PMC12467108

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