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Article

MCRS1 is essential for epiblast development during early mouse embryogenesis.

Reproduction (Cambridge, England) - 1 Jan 2020

Cui Wei, Cheong Agnes, Wang Yongsheng, Tsuchida Yuran, Liu Yong, Tremblay Kimberly D, Mager Jesse

Abstract excerpt

Microspherule protein 1 (MCRS1, also known as MSP58) is an evolutionarily conserved protein that has been implicated in various biological processes. Although a variety of functions have been attributed to MCRS1 in vitro, mammalian MCRS1 has not been studied in vivo. Here we report that MCRS1 is essential during early murine development. Mcrs1 mutant embryos exhibit normal morphology at the blastocyst stage but...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31671403
DOI: 10.1530/REP-19-0334
PMCID: PMC7431978

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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