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Article

EMG1 is essential for mouse pre-implantation embryo development.

BMC developmental biology - 21 Sept 2010

Wu Xiaoli, Sandhu Sumit, Patel Nehal, Triggs-Raine Barbara, Ding Hao

Abstract excerpt

BACKGROUND: Essential for mitotic growth 1 (EMG1) is a highly conserved nucleolar protein identified in yeast to have a critical function in ribosome biogenesis. A mutation in the human EMG1 homolog causes Bowen-Conradi syndrome (BCS), a developmental disorder characterized by severe growth failure and psychomotor retardation leading to death in early childhood. To begin to understand the role of EMG1 in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20858271
DOI: 10.1186/1471-213X-10-99
PMCID: PMC2954994

Genes

EMG1

Provenance

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