Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An Interethnic Comparison of Polymorphisms of the Genes Encoding Drug-Metabolizing Enzymes and Drug Transporters: Experience in Singapore

1 Jan 2005

Abstract excerpt

Much of the interindividual variability in drug response is attributable to the presence of single nucleotide polymorphisms (SNPs) in genes encoding drug-metabolizing enzymes and drug transporters. In recent years, we have investigated the polymorphisms in a number of genes encoding phase I and II drug-metabolizing enzymes including CYPIA1, CYP3A4, CYP3A5, GSTM1, NAT2, UGT1A1, and TPMT and drug transporter (MDR1)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Pharmacogenetics and Drug Metabolism
Share to Pharmacological Effects and Toxicity Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15931768
DOI: 10.1081/dmr-28805

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An Interethnic Comparison of Polymorphisms of the Genes Encoding Drug-Metabolizing Enzymes and Drug Transporters: Experience in SingaporePMID 15931768Read ↗

Pharmacogenetics of common SNP affecting drug metabolizing enzymes: comparison of allele frequencies between European and Malaysian/Singaporean.Semantic proximity Read ↗

Pharmacogenetics of CYP1A2, novel polymorphisms and haplotypes in three distinct Asian populations.Semantic proximity Read ↗

Inter and intra-ethnic differences in the distribution of the molecular variants of TPMT, UGT1A1 and MDR1 genes in the South Indian population.Semantic proximity Read ↗

Distribution of genetic polymorphisms of genes encoding drug metabolizing enzymes & drug transporters - a review with Indian perspective.Semantic proximity Read ↗

Genetic variations of the ABCC2 gene in the Chinese, Malay, and Indian populations of Singapore.Semantic proximity Read ↗

Interethnic comparisons of important pharmacology genes using SNP databases: potential application to drug regulatory assessments.Semantic proximity Read ↗

Genetic variations of the SLCO1B1 gene in the Chinese, Malay and Indian populations of Singapore.Semantic proximity Read ↗

Pharmacogenomic diversity in Singaporean populations and Europeans.Semantic proximity Read ↗

Genetic polymorphisms of drug-metabolizing phase I enzymes CYP2E1, CYP2A6 and CYP3A5 in South Indian population.Semantic proximity Read ↗

Pharmacogenetic risk for adverse reactions to irinotecan in the major ethnic populations of Singapore: regulatory evaluation by the health sciences authority.Semantic proximity Read ↗

CYP3A5*3 and *6 single nucleotide polymorphisms in three distinct Asian populations.Semantic proximity Read ↗

Genotyping of eight polymorphic genes encoding drug-metabolizing enzymes and transporters using a customized oligonucleotide array.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.