Article
CYP3A5*3 and *6 single nucleotide polymorphisms in three distinct Asian populations.
European journal of clinical pharmacology - 1 Jun 2003
Balram C, Zhou Qingyu, Cheung Yin Bun, Lee Edmund J D
Abstract excerpt
OBJECTIVE: To determine the frequencies of two functional single nucleotide polymorphisms, CYP3A5*3 and CYP3A5*6, in the CYP3A5 gene in three distinct Asian ethnic groups, namely, the Chinese, Malays and Indians. METHODS: Single nucleotide polymorphism analyses of CYP3A5*1, *3 and *6 were performed in 296 healthy subjects (108 Chinese, 98 Malays and 90 Indians) using the polymerase chain reaction-restriction...
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