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Pharmacogenetics of common SNP affecting drug metabolizing enzymes: comparison of allele frequencies between European and Malaysian/Singaporean.

Drug metabolism and personalized therapy - 19 Mar 2021

Bakar Nur Salwani

Abstract excerpt

Compared to Europe, data on genetic variation in genes transcribing drug metabolizing enzymes among Asian is limited due to ethnic diversity. Here we compare frequencies for clinically relevant single nucleotide polymorphism (SNP) commonly observed in drug metabolizing enzymes between European and Malaysian/Singaporean. Minor allele frequencies (MAF) for the indicated SNPs for European, South Asian and East Asian...

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Arylamine N-Acetyltransferase
Cytochrome P-450 CYP2C19
Cytochrome P-450 CYP2D6
Gene Frequency
Pharmacogenetics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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PMID: 34412170
DOI: 10.1515/dmpt-2020-0153

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