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Article

Distribution of genetic polymorphisms of genes encoding drug metabolizing enzymes & drug transporters - a review with Indian perspective.

The Indian journal of medical research - 1 Jan 2014

Umamaheswaran Gurusamy, Kumar Dhakchinamoorthi Krishna, Adithan Chandrasekaran

Abstract excerpt

Phase I and II drug metabolizing enzymes (DME) and drug transporters are involved in the absorption, distribution, metabolism as well as elimination of many therapeutic agents, toxins and various pollutants. Presence of genetic polymorphisms in genes encoding these proteins has been associated with marked inter-individual variability in their activity that could result in variation in drug response, toxicity as...

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Identifiers

PMID: 24604039
PMCID: PMC3994740

Genes

COMT
NAT2
TPMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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