Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of catechol-O-methyltransferase with smoking cessation in two independent studies of women

1 Jun 2005

Abstract excerpt

OBJECTIVES AND METHODS: The Val108/158Met polymorphism in the gene that encodes COMT, a dopamine metabolizing enzyme, results in a three- to four-fold reduction in COMT activity. To determine if the lower activity Met allele of COMT was associated with smoking cessation in women, we used two independent studies: a population-based case--control study and a nicotine replacement clinical trial. RESULTS: In the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neurotransmitter Receptor Influence on Behavior
Share to Smoking Behavior and Cessation
Share to Substance Abuse Treatment and Outcomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15900212
DOI: 10.1097/01213011-200506000-00004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of catechol-O-methyltransferase with smoking cessation in two independent studies of womenPMID 15900212Read ↗

Association of COMT Val108/158Met genotype with smoking cessation in a nicotine replacement therapy randomized trial.Semantic proximity Read ↗

Association between catechol-O-methyltransferase (COMT) Val/Met genotype and smoking cessation treatment with nicotine: a meta-analysis.Semantic proximity Read ↗

The effect of catechol-O-methyltransferase Met/Val functional polymorphism on smoking cessation: retrospective and prospective analyses in a cohort study.Semantic proximity Read ↗

Association of COMT Val108/158Met genotype with smoking cessation.Semantic proximity Read ↗

Variants in COMT and spontaneous smoking cessation: retrospective cohort analysis of 925 cessation events.Semantic proximity Read ↗

Association study of a functional catechol-O-methyltransferase polymorphism and smoking in healthy Caucasian subjects.Semantic proximity Read ↗

Association of functional COMT Val108/Met polymorphism with smoking cessation in a nicotine replacement therapy.Semantic proximity Read ↗

Association of COMT Val(108/158)Met genotype and cigarette smoking in pregnant women.Semantic proximity Read ↗

Catechol-O-methyltransferase gene methylation and substance use in adolescents: the TRAILS study.Semantic proximity Read ↗

Association of abstinence-induced alterations in working memory function and COMT genotype in smokers.Semantic proximity Read ↗

Significant association of catechol-O-methyltransferase (COMT) haplotypes with nicotine dependence in male and female smokers of two ethnic populations.Semantic proximity Read ↗

Association of functional catechol O-methyl transferase (COMT) Val108Met polymorphism with smoking severity and age of smoking initiation in Chinese male smokers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.