Article
The effect of catechol-O-methyltransferase Met/Val functional polymorphism on smoking cessation: retrospective and prospective analyses in a cohort study.
Pharmacogenetics and genomics - 1 Jan 2009
Omidvar Maryam, Stolk Lisette, Uitterlinden Andre G, Hofman Albert, Van Duijn Cornelia M, Tiemeier Henning
Abstract excerpt
OBJECTIVE: The Met/Val functional polymorphism of the gene-encoding catechol-O-methyltransferase (COMT) is one of the most widely tested variants for association with different phenotypes of addictive behavior, but replication has been inconsistent for smoking status. We investigated the relationship of this COMT single nucleotide polymorphism with smoking cessation in elderly persons in retrospective and...
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