Article
Association of COMT Val(108/158)Met genotype and cigarette smoking in pregnant women.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Feb 2011
Munafò Marcus R, Freathy Rachel M, Ring Susan M, St Pourcain Beate, Smith George Davey
Abstract excerpt
INTRODUCTION: Smoking behaviors, including heaviness of smoking and smoking cessation, are known to be under a degree of genetic influence. The enzyme catechol O-methyltransferase (COMT) is of relevance in studies of smoking behavior and smoking cessation due to its presence in dopaminergic brain regions. While the COMT gene is therefore one of the more promising candidate genes for smoking behavior, some...
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