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Article

Association between catechol-O-methyltransferase (COMT) Val/Met genotype and smoking cessation treatment with nicotine: a meta-analysis.

Pharmacogenomics - 1 Nov 2015

Choi Hye Duck, Shin Wan Gyoon

Abstract excerpt

AIM: Catechol-O-methyltransferase (COMT) is one of the major degradative pathways of dopamine and COMT Val/Met polymorphisms are associated with the enzyme activity, which is related to dopamine involvement in the nicotine addiction process. However, the reported results of several genetic studies are not consistent. MATERIALS & METHODS: We reviewed the smoking cessation outcomes among previously reported studies...

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Identifiers

PMID: 26555332
DOI: 10.2217/pgs.15.127

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association between catechol-O-methyltransferase (COMT) Val/Met genotype and smoking cessation treatment with nicotine: a meta-analysis.PMID 26555332Read ↗

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