Article
Association study of a functional catechol-O-methyltransferase polymorphism and smoking in healthy Caucasian subjects.
Neuroscience letters - 12 Apr 2010
Nedic Gordana, Nikolac Matea, Borovecki Fran, Hajnsek Sanja, Muck-Seler Dorotea, Pivac Nela
Abstract excerpt
Tobacco smoking is a global health problem. The association of a functional common polymorphism in the catechol-o-methyltransferase gene (COMT Val158Met) with smoking behavior has been extensively studied, but with divergent findings. In the present study the frequency of COMT genotypes and alleles was evaluated in 578 male and a smaller group of 79 female unrelated, medication-free Caucasian healthy subjects of...
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