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Article

Single nucleotide polymorphisms of the IL18 gene are associated with atopic eczema.

The Journal of allergy and clinical immunology - 1 Apr 2005

Novak Natalija, Kruse Susanne, Potreck Jana, Maintz Laura, Jenneck Claudia, Weidinger Stephan, Fimmers Rolf, Bieber Thomas

Abstract excerpt

BACKGROUND: Human IL-18 is an inflammatory cytokine that plays a role in atopic diseases, such as atopic eczema (AE), by enhancing IL-4 and IL-13 production and stimulating the synthesis of IgE. OBJECTIVE: To evaluate associations of polymorphisms in the IL18 gene on chromosome 11q22 with AE, we performed genotyping for single nucleotide polymorphisms (SNPs) in the IL18 gene in 225 patients with AE and 175...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 15806006
DOI: 10.1016/j.jaci.2005.01.030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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