Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The common G-allele of interleukin-18 single-nucleotide polymorphism is a genetic risk factor for atopic asthma. The SAPALDIA Cohort Study.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Feb 2006

Imboden M, Nicod L, Nieters A, Glaus E, Matyas G, Bircher A J, Ackermann-Liebrich U, Berger W, Probst-Hensch N M

Abstract excerpt

BACKGROUND: IL-18 is a pleiotrophic cytokine involved in both, T-helper type 1 (Th1) and Th2 differentiation. Recently genetic variants in the IL-18 gene have been associated with increased risk of atopy and asthma. OBJECTIVE: To examine the relationship of a genetic, haplotype-tagging promotor variant -137G/C in the IL-18 gene with atopic asthma in a large, well-characterized and population-based study of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma
Share to Hypersensitivity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-18

Share to Logistic Models

Share to Odds Ratio

Share to Promoter Regions, Genetic

Share to Skin Tests

Share to Switzerland

Source

Identifiers

PMID: 16433859
DOI: 10.1111/j.1365-2222.2006.02424.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The common G-allele of interleukin-18 single-nucleotide polymorphism is a genetic risk factor for atopic asthma. The SAPALDIA Cohort Study.PMID 16433859Read ↗

Interleukin-18 promoter polymorphism in patients with atopic asthma.Semantic proximity Read ↗

Polymorphisms in the IL 18 gene are associated with specific sensitization to common allergens and allergic rhinitis.Semantic proximity Read ↗

Protective role of IL-18 -137G/C polymorphism in a North Indian population with asthma: a pilot study.Semantic proximity Read ↗

Association between interleukin-18 gene polymorphism 105A/C and asthma.Semantic proximity Read ↗

Interleukin-18 genetics and inflammatory disease susceptibility.Semantic proximity Read ↗

Interleukin-18 promoter polymorphism and asthma risk: a meta-analysis.Semantic proximity Read ↗

Variants in the IL17 pathway genes are associated with atopic asthma and atopy makers in a South American populationSemantic proximity Read ↗

Single nucleotide polymorphisms of the IL18 gene are associated with atopic eczema.Semantic proximity Read ↗

A Functional Polymorphism in IL-18 Is Associated with Severity of Bronchial AsthmaSemantic proximity Read ↗

Haplotype analysis of the interleukin-18 gene in Czech patients with allergic disorders.Semantic proximity Read ↗

Association of interleukin-18 gene polymorphism with asthma in Chinese patients.Semantic proximity Read ↗

Association of the single-nucleotide polymorphism and haplotype of the interleukin 18 gene with atopic dermatitis in Koreans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.