Interleukin-18 gene polymorphisms in Egyptian patients with allergic diseases.

doi:10.2500/ajra.2012.26.3806

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Article

Interleukin-18 gene polymorphisms in Egyptian patients with allergic diseases.

American journal of rhinology & allergy - 1 Jan 2000

Ibrahim Gehan H, ElTabbakh Mohammed T, Gomaa Amal H A, Mohamed Eman A

Abstract excerpt

BACKGROUND: Allergic diseases, such as allergic rhinitis (AR) and atopic dermatitis (AD), affect a large proportion of people worldwide. Both have environmental and genetic predisposing factors. Single nucleotide polymorphisms (SNPs) in interleukin (IL)-18, may play a direct role in the disease pathogenesis. This study was designed to investigate the association of the IL-18 gene SNPs (-137 G/C [rs187238], and...

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PMID: 22840759
DOI: 10.2500/ajra.2012.26.3806

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