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Article

Association of the single-nucleotide polymorphism and haplotype of the interleukin 18 gene with atopic dermatitis in Koreans.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jun 2007

Kim E, Lee J-E, Namkung J-H, Park J-H, Kim S, Shin E-S, Cho E-Y, Yang J-M

Abstract excerpt

BACKGROUND: IL-18 is a proinflammatory cytokine that plays an important role for T-helper type 1 (Th1) and Th2 cytokine in the presence/absence of IL-12. It has been recently shown that human IL-18 plays a role in atopic dermatitis (AD) by enhancing IL-4 and IL-13 production and by stimulating the synthesis of IgE. OBJECTIVE: We wanted to evaluate the associations of single-nucleotide polymorphism (SNP) and the...

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Identifiers

PMID: 17517100
DOI: 10.1111/j.1365-2222.2007.02717.x

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