Article
Association between interleukin 18 polymorphisms and alopecia areata in Koreans.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 May 2014
Kim Su Kang, Park Hae Jeong, Chung Joo-Ho, Kim Jong Woo, Seok Hosik, Lew Bark-Lynn, Sim Woo-Young
Abstract excerpt
Interleukin 18 (interferon gamma-inducing factor) (IL18) is an important proinflammatory cytokine that belongs to the IL1 family. This study investigated whether IL18 single-nucleotide polymorphisms (SNPs) are associated with the susceptibility to alopecia areata (AA) in a Korean population. Two hundred thirty-three AA patients and 243 healthy control subjects were recruited. One promoter SNP (rs187238, -137G/C)...
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