Article
Interleukin-18 and its three gene polymorphisms relating to allergic rhinitis.
Journal of human genetics - 1 Jan 2007
Sebelova Sarka, Izakovicova-Holla Lydie, Stejskalova Andrea, Schüller Marcel, Znojil Vladimir, Vasku Anna
Abstract excerpt
The study aimed to examine an association of three different single nucleotide polymorphisms (SNPs) of the IL-18 gene (-607 C/A, -137 G/C and -133 C/G) on chromosome 11q22 with allergic rhinitis (AR). Genotyping for the SNPs was performed using 539 patients with AR and 312 healthy control volunteers. Positivity to the skin prick test for the fungus Alternaria sp. in patients with AR, and IgE levels according to...
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