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Article

The impact of IL18 gene polymorphisms on mRNA levels and interleukin-18 release by peripheral blood mononuclear cells.

Postepy higieny i medycyny doswiadczalnej (Online) - 20 Jun 2012

Dziedziejko Violetta, Kurzawski Mateusz, Paczkowska Edyta, Machalinski Bogusław, Pawlik Andrzej

Abstract excerpt

INTRODUCTION: Interleukin-18 (IL-18) is a pleiotropic cytokine playing an important role as a modulator of immune responses, found to play a role in pathogenesis of numerous inflammatory-associated disorders. In the present study a potential association between 7 common single-nucleotide polymorphisms (SNPs) spanning the whole IL18 gene, gene expression and the release of IL-18 from the stimulated peripheral...

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PMID: 22922140
DOI: 10.5604/17322693.1000980

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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