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Article

Interleukin-18 genetics and inflammatory disease susceptibility.

Genes and immunity - 1 Mar 2007

Thompson S R, Humphries S E

Abstract excerpt

IL18 was mapped to 11q22.2-22.3 in 1998. Owing to interleukin (IL)-18's important and novel role in immunomodulation, the gene itself has been subject to scrutiny, with the aim of discovering variants that may impact on disease susceptibility and/or progression. Despite being sequenced numerous times in different populations, no non-synonymous variants have been found. However, a number of polymorphisms within...

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Identifiers

PMID: 17215860
DOI: 10.1038/sj.gene.6364366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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