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Article

Polymorphisms in the IL 18 gene are associated with specific sensitization to common allergens and allergic rhinitis.

The Journal of allergy and clinical immunology - 1 Jan 2003

Kruse Susanne, Kuehr Joachim, Moseler Michael, Kopp Matthias V, Kurz Thorsten, Deichmann Klaus A, Foster Paul S, Mattes Joerg

Abstract excerpt

BACKGROUND: Atopy has been linked to chromosome 11q22, a region that harbors the IL18 gene. IL-18 enhances IL-4/IL-13 production and induces IgE production that is directly associated with the pathogenesis of atopic disorders. OBJECTIVE: We sought to investigate whether genetic abnormalities in the regulatory regions of the IL18 gene predispose, in part, to susceptibility to atopy. METHODS: Among a white...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12532106
DOI: 10.1067/mai.2003.43

Genes

GATA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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