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Article

Individual growth curve analysis of APOE epsilon 4-associated cognitive decline in Alzheimer disease.

Archives of neurology - 1 Mar 2005

Hoyt Brian D, Massman Paul J, Schatschneider Christopher, Cooke Norma, Doody Rachelle S

Abstract excerpt

BACKGROUND: The apolipoprotein E epsilon4 (APOE epsilon4) allele is associated with an increased risk of developing Alzheimer disease (AD). However, findings regarding an association between the APOE epsilon4 allele and the rate of decline in AD have been mixed. OBJECTIVE: To examine the relationship between the APOE epsilon4 allele and the rate of cognitive and functional decline in AD using individual growth...

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Identifiers

PMID: 15767511
DOI: 10.1001/archneur.62.3.454

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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