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Article

APOE alleles predict the rate of cognitive decline in Alzheimer disease: a nonlinear model.

Neurology - 27 Dec 2005

Martins C A R, Oulhaj A, de Jager C A, Williams J H

Abstract excerpt

BACKGROUND: The APOE genotype predicts the age at onset of Alzheimer disease (AD) and neuropathologic progression. However, studies relating APOE alleles to the rate of cognitive decline have been inconclusive. This may stem from their use of linear statistical analyses. OBJECTIVE: To model relations of APOE alleles to the rate of cognitive decline in AD, nonlinearly. METHODS: Serial measures of cognitive ability...

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Source

Identifiers

PMID: 16380608
DOI: 10.1212/01.wnl.0000188871.74093.12

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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