Article
Separation of sister chromatids in mitosis requires the Drosophila pimples product, a protein degraded after the metaphase/anaphase transition.
Cell - 12 Jan 1996
Stratmann R, Lehner C F
Abstract excerpt
Mutations in the Drosophila genes pimples and three rows result in a defect of sister chromatid separation during mitosis. As a consequence, cytokinesis is also defective. However, cell cycle progression including the mitotic degradation of cyclins A and B is not blocked by the failure of sister...
Topics
- Amino Acid Sequence
- Anaphase
- Animals
- Antigens, Protozoan
- Base Sequence
- Blotting, Northern
- Cell Cycle Proteins
- Cell Division
- Centromere
- Chromatids
- Chromosomes
- Cloning, Molecular