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Article

Genetic interactions of separase regulatory subunits reveal the diverged Drosophila Cenp-C homolog.

Genes & development - 1 Sept 2005

Heeger Sebastian, Leismann Oliver, Schittenhelm Ralf, Schraidt Oliver, Heidmann Stefan, Lehner Christian F

Abstract excerpt

Faithful transmission of genetic information during mitotic divisions depends on bipolar attachment of sister kinetochores to the mitotic spindle and on complete resolution of sister-chromatid cohesion immediately before the metaphase-to-anaphase transition. Separase is thought to be responsible for sister-chromatid separation, but its regulation is not completely understood. Therefore, we have screened for...

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Identifiers

PMID: 16140985
DOI: 10.1101/gad.347805
PMCID: PMC1199574

Genes

CENPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic interactions of separase regulatory subunits reveal the diverged Drosophila Cenp-C homolog.PMID 16140985Read ↗

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