Genetic interactions between Cdk1-CyclinB and the Separase complex in Drosophila.

doi:10.1242/dev.01780

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Article

Genetic interactions between Cdk1-CyclinB and the Separase complex in Drosophila.

Development (Cambridge, England) - 1 Apr 2005

Ji Jun-Yuan, Crest Justin, Schubiger Gerold

Abstract excerpt

Cdk1-CycB plays a key role in regulating many aspects of cell-cycle events, such as cytoskeletal dynamics and chromosome behavior during mitosis. To investigate how Cdk1-CycB controls the coordination of these events, we performed a dosage-sensitive genetic screen, which is based on the observations that increased maternal CycB (four extra gene copies) leads to higher Cdk1-CycB activity in early Drosophila...

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PMID: 15772129
DOI: 10.1242/dev.01780

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.