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Article

Separase is required for chromosome segregation during meiosis I in Caenorhabditis elegans.

Current biology : CB - 27 Nov 2001

Siomos M F, Badrinath A, Pasierbek P, Livingstone D, White J, Glotzer M, Nasmyth K

Abstract excerpt

BACKGROUND: Chromosome segregation during mitosis and meiosis is triggered by dissolution of sister chromatid cohesion, which is mediated by the cohesin complex. Mitotic sister chromatid disjunction requires that cohesion be lost along the entire length of chromosomes, whereas homolog segregation at meiosis I only requires loss of cohesion along chromosome arms. During animal cell mitosis, cohesin is lost in two...

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PMID: 11728305
DOI: 10.1016/s0960-9822(01)00588-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Separase is required for chromosome segregation during meiosis I in Caenorhabditis elegans.PMID 11728305Read ↗

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Separase Cleaves the N-Tail of the CENP-A Related Protein CPAR-1 at the Meiosis I Metaphase-Anaphase Transition in C. elegans.Semantic proximity Read ↗

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