Article
Linkage analysis using single nucleotide polymorphisms.
Human heredity - 1 Jan 2004
Browning Brian L, Brashear Donna L, Butler Andy A, Cyr Devon D, Harris Elizabeth C, Nelsen Anita J, Yarnall David P, Ehm Margaret G, Wagner Michael J
Abstract excerpt
We performed multipoint linkage analysis using 83 markers from the SNP Consortium (TSC) SNP linkage map in 3 regions covering 190 cM previously scanned with microsatellite markers and found to be linked to type 2 diabetes. Since the average linkage disequilibrium present in the TSC SNP marker clusters is relatively low, we assumed the intracluster genetic distances were a reasonable small nonzero distance (0.03...
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