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Article

Linkage and association analyses of microsatellites and single-nucleotide polymorphisms in nuclear families.

BMC genetics - 30 Dec 2005

Lin Jennifer, Liu Kuang-Yu

Abstract excerpt

Several simulation studies have suggested that a high-density single-nucleotide polymorphisms (SNPs) marker set may be as useful as a traditional microsatellites (MS) marker set in performing whole-genome linkage analysis. However, very few studies have directly tested the SNPs-based genome-wide scan. In the present study, we compared the linkage results from the SNPs-based scan with a map density of 3-cM spacing...

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PMID: 16451634
DOI: 10.1186/1471-2156-6-S1-S25
PMCID: PMC1866761

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NPL

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