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Article

Multi-marker linkage disequilibrium mapping of quantitative trait loci.

Briefings in bioinformatics - 1 Mar 2017

Lee Soyoun, Yang Jie, Huang Jiayu, Chen Hao, Hou Wei, Wu Song

Abstract excerpt

Single nucleotide polymorphisms (SNPs), the most common genetic markers in genome-wide association studies, are usually in linkage disequilibrium (LD) with each other within a small genomic region. Both single- and two-marker-based LD mapping methods have been developed by taking advantage of the LD structures. In this study, a more general LD mapping framework with an arbitrary number of markers has been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26966282
DOI: 10.1093/bib/bbw006
PMCID: PMC5862291

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