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Article

Phenotypical and functional alterations in the mucosal immune system of CD45 exon 9 KO mice.

International immunology - 1 Jan 2005

López María C, Holmes Nick

Abstract excerpt

The protein tyrosine phosphatase CD45 has been shown to be an important regulator of antigen-receptor signaling in both T and B lymphocytes. Lymphocyte populations within the gut mucosa are phenotypically and ontogenetically different from those generally found in secondary lymphoid tissue. In T lymphopenic mice, extrathymic T cell development takes place within the gut. Here we report the characterization of T...

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Share to Antigens, Surface
Share to CD4-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Intestinal Mucosa

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Share to Receptors, Antigen, T-Cell, alpha-beta

Share to Receptors, Antigen, T-Cell, gamma-delta

Share to T-Lymphocyte Subsets

Source

Identifiers

PMID: 15557316
DOI: 10.1093/intimm/dxh181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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