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[Early T cell development in gene-targeted mutant mice].

Sheng li ke xue jin zhan [Progress in physiology] - 1 Apr 1997

Yu Q, Chen W F

Abstract excerpt

Early intrathymic T cell development is highly coordinated and controlled by the interaction of a variety of molecules. The development of gene targeting technology provided a valuable tool to study the function of these molecules in vivo. The analysis of TCR and CD3 gene targeted mice indicated that CD44-CD25+ is a control point in early T cell development. At this stage, the expression of pre-TCR complex...

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PMID: 11038702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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