Article

CD45 limits Natural Killer cell development from common lymphoid progenitors

2023-04-17

Abstract excerpt

The clinical development of Natural Killer (NK) cell-mediated immunotherapy marks a milestone in the development of new cancer therapies and has gained traction due to the intrinsic ability of the NK cell to target and kill tumour cells. To fully harness the tumour killing ability of NK cells, we need to improve NK cell persistence and overcome suppression of NK cell activation in the tumour microenvironment. The...

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Literature Corpus work: 54a9434f-69d5-5ce0-afeb-d3164fb79f22
DOI: 10.1101/2023.04.17.537109

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